Biological Treatments

 

For patients seeking alternatives to surgery or looking to enhance their body’s natural healing process, biological treatments offer a cutting-edge, regenerative approach to orthopedic care. At Dr. Michael Sileo’s office, the latest advancements in biological medicine are used to promote healing, reduce inflammation, and improve quality of life for patients with a wide range of musculoskeletal conditions.

These treatments harness the body’s own regenerative capabilities — minimizing downtime and supporting long-term recovery. 

Conditions Treated with Biological Treatments

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Comprehensive care for a wide spectrum of  issues, from acute sports injuries to chronic degenerative conditions.

Hip Pain (1)

Osteoarthritis

Biological treatments, including PRP and stem cell therapy, are used to manage osteoarthritis of the knee, hip, shoulder, and other joints — reducing inflammation, slowing cartilage breakdown, and improving joint function without surgical intervention.
Sports Injury

Tendon Injuries

Conditions such as Achilles tendonitis, rotator cuff tears, and tennis elbow respond well to PRP injections, which accelerate tendon healing and reduce chronic inflammation that often resists traditional treatment approaches. Early biological treatment can help avoid surgery.
Knee Pain (3)

Ligament Injuries

ACL tears, MCL tears, and other ligament injuries can benefit from biological treatments as part of a broader non-surgical management plan or to support healing following surgical reconstruction. PRP therapy is commonly used to enhance recovery and improve long-term outcomes.
Knee Pain (3)

Sports Injuries

Sprains, strains, and a broad range of sports-related orthopedic conditions are frequently managed with PRP and regenerative therapies, helping athletes recover faster and return to sport with less downtime. Biological treatments are increasingly recognized as a key component of modern sports medicine recovery.
Knee Pain (3)

Cartilage Damage

Articular cartilage defects and injuries — which have limited natural healing capacity — can be treated with biological approaches to promote regeneration and reduce pain in affected joints. These treatments offer a valuable option for patients looking to preserve joint function and delay or avoid surgery.
Close up illustration of a DNA double helix strand, highlighting the foundation of biological treatments, with a blurred background featuring additional DNA strands and soft glowing lights

Biological Treatments

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  • Platelet-Rich Plasma (PRP) Treatment Platelet-rich plasma (PRP) is derived from the patient's own blood and contains a higher concentration of platelets, growth factors, and bioactive proteins than normal blood. When injected into the affected area, PRP stimulates the body's natural healing processes, accelerates tissue repair, and reduces inflammation. PRP is derived from the patient's own blood, it carries a low risk of adverse reaction and is well tolerated by most patients. PRP is commonly used for tendon injuries, ligament damage, cartilage conditions, and osteoarthritis — and is frequently incorporated into both non-surgical treatment plans and post-surgical recovery protocols to optimize healing outcomes.
  • Stem Cell Therapy Stem cell therapy is a regenerative medical procedure that utilizes the body's natural healing ability. Stem cells have the remarkable potential to develop into various cell types — including bone, cartilage, and muscle cells — making them a powerful tool for promoting tissue repair and reducing inflammation in damaged joints and soft tissue. By harnessing this regenerative potential, stem cell therapy can alleviate pain and support recovery from a range of orthopedic conditions without the need for surgery.

Our Treatment Approach

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Comprehensive Evaluation

A thorough physical examination, complete medical history review, and advanced imaging — including X-ray and MRI — are used to accurately assess your condition and determine whether biological treatments are appropriate for your specific situation.

Conservative Treatment

Every patient is unique. Dr. Sileo tailors biological treatment plans to address each patient’s specific condition, medical history, and personal goals — ensuring the most appropriate regenerative approach is carefully selected for optimal and lasting results.

Patient-Centered
Care

Open communication and active patient involvement in decision-making are central to every treatment plan. You will always be fully informed about your options, the evidence behind each treatment, and what to expect throughout your care.

Integrated Recovery Support

Biological treatments are most effective when combined with physical therapy and rehabilitation. A recovery plan incorporating both regenerative treatments and structured rehabilitation maximizes outcomes and supports long-term joint health.

Recovery After Biological Treatments

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Recovery following PRP and stem cell therapy is generally straightforward, though timelines vary depending on the condition treated and the patient’s individual response.

Stem Cell Therapy
Days 1-7Mild soreness at the injection or harvest site is common. Rest and limited activity are recommended during this initial phase.
Weeks 2-6The regenerative process begins as stem cells work to repair damaged tissue. Gradual improvement in symptoms is typically experienced during this phase.
3-6 MonthsMost patients experience meaningful improvement in pain and function. Full results from stem cell therapy may continue to develop over several months as tissue regeneration progresses.
PRP Injections
Days 1-3Mild soreness and swelling at the injection site are normal and typically resolve within a few days. Activity is usually restricted during this period to allow the platelets to begin working.
Weeks 1-4 Most patients begin to notice gradual improvement in pain and function as the healing process progresses. Full benefit from PRP often takes several weeks to become apparent.
1-3 Months Meaningful improvement in pain, inflammation, and function is typically experienced during this phase. Some patients require a series of injections for optimal results.

Frequently Asked Questions

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What is the difference between PRP and stem cell therapy?

PRP uses concentrated platelets from the patient’s own blood to deliver growth factors directly to the injured area, stimulating the body’s natural healing response. Stem cell therapy uses cells with the ability to develop into multiple tissue types — including cartilage, bone, and muscle — to promote more extensive tissue regeneration. Both treatments are minimally invasive and use the patient’s own biological material, but they work through different mechanisms and are suited to different conditions and severity levels. Dr. Sileo will recommend the most appropriate option based on your specific diagnosis and goals.

Are biological treatments a replacement for surgery?

For some patients and conditions, biological treatments can effectively manage symptoms and promote healing without the need for surgery. For others, they are best used as a complement to surgical treatment — either to optimize the healing environment before surgery or to accelerate recovery afterward. The appropriateness of biological treatments as a standalone approach depends on the severity of the condition, the patient’s overall health, and their individual goals. A comprehensive evaluation is needed to determine the right course of care.

How many PRP injections will I need?

The number of PRP injections needed varies depending on the condition being treated and the patient’s individual response. Some patients experience significant improvement after a single injection, while others benefit from a series of two to three injections spaced several weeks apart. Dr. Sileo will develop a personalized treatment plan based on your specific condition and monitor your progress to determine the most effective protocol for your situation.

Are biological treatments covered by insurance?

Biological treatments, including PRP and stem cell therapy, are not currently covered by most insurance plans, as they are considered investigational or elective by many carriers. The office team can provide detailed information on treatment costs and available payment options during your consultation. Many patients find that the benefits of these treatments — including reduced downtime, avoided surgery, and faster recovery — make them a worthwhile investment in their long-term health.

Where to Get Biological Treatments on Long Island

Dr. Sileo sees patients at two convenient Long Island locations. New patients are welcome.

Commack Office

312A Commack Rd
Commack, NY 11725

East Setauket Office

6 Technology Drive, Suite 100
East Setauket, NY 11733

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Take the first step towards recovery.

(631) 689-4189(631) 689-4189
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  • Office hours: Mon-Fri, 8:00 AM - 5:00 PM